Prenatal diagnosis of a rare heteropagus

The prenatal diagnosis by ultrasound of an unusual case of supernumerary head is reported. The problems of differential diagnosis, the pathological findings after voluntary interruption of the pregnancy, and the problems of obstetric management are presented.     

The safety of fetoscopy: (I). Effect of umbilical vessel puncture on the fetal heart rate and cord histology

The fetal heart rate (FHR) was continuously monitored during 42 umbilical vessel punctures performed at the placental insertion of the cord in 24 diagnostic fetoscopies in which pure fetal blood was obtained. In only one patient did a deceleration first appear during puncture and aspiration of fetal blood. In two patients decelerations preceded fetoscopy and in two others they began during the fetoscopy but before puncture of an umbilical vessel. In 19 patients, the FHR did not change at all during the procedure. Fetal haemorrhage after sampling was either absent or minimal. Six pregnancies were terminated because a positive diagnosis had been made and 18 healthy babies were born. Umbilical cords were examined after 7 terminations of pregnancy and after 6 deliveries. In the former group the puncture could just be seen with the naked eye and the needle track was demonstrated histologically in 6. No traces of the puncture or other abnormalities were found in the cords after delivery. Fetal blood sampling from umbilical cord vessels, particularly at the placental insertion of the cord, is the technique of choice since pure fetal blood can be obtained without increasing the risk of fetoscopy.     

Tectonic and lithological constraints on the evolution of the Karoo graben of northern Malawi (East Africa)

The results of a lithostratigraphic, tectonic and kinematic study of the Karoo deposits of northern Malawi are reported. The objective of the lithostratigraphic study is to correlate the deposits of the Karoo basins of northern Malawi with the well-known deposits of southern Tanzania, thus establishing a stratigraphic framework through which the timing of faulting can be constrained. The kinematic analysis of faulting constrains the opening direction for the Karoo graben in this area and provides basic data to discuss the Karoo graben development within the regional tectonic framework of south-eastern Africa. The studied faults are defined by moderately to steeply dipping cataclastic zones with a width of up to 15?m and are characterized by an array of slickensided fault surfaces with different orientations and slip directions. In this study, small faults (offset <10?m) and meso-scale faults (offset >10?m, but generally not exceeding 30–40?m) have been distinguished. Methods used to analyse the kinematic data include the 'pressure tension' (PT) method, which estimates the principal axes for the bulk brittle strain, and the internal rotation axis (IRA) method, which estimates the axis of bulk internal rotation and the overall sense of slip at the faults. A mass balance calculation reveals a volume increase of up to 16% during cataclastic deformation in the fault zones. The PT method shows an approximately east trending extension direction for faults that occur only in the latest Carboniferous (?) and Early Permian strata, whereas the fault kinematics from faults that cut middle Permian to Early Triassic rocks is characterized by a ESE to SE trending extension direction. The small faults yield essentially the same kinematic results as the meso-scale faults. In a transport-parallel cross-sectional view, the principal extension axes are at an acute angle of approximately 60° to the major fault planes. Given the moderate fault density, the relatively high angle between the orientation of the principal extension axis and the fault planes suggest only a moderate amount of horizontal extension across the Karoo graben of northern Malawi. Riedel structures in the fault zones formed within two conjugate sets of localized shear zones; slip on one set was top to the W/NW and, on the other, top to the E/SE. The two conjugate sets of Riedel structures have an acute angle about the regional shortening axes, implying that no pronounced rotation of the strain axes occurred. The internal rotation axes for the Riedel structures reveal a largely bimodal distribution and inferred weakly monoclinic to orthorhombic symmetry. Therefore the overall deformation during Karoo rifting in northern Malawi is interpreted to be close to a coaxial deformation with a limited amount of horizontal extension.     

Gas chromatographic separation and determination of chloroanthracene isomers on fly ash

An efficient, reproducible and rapid fused silica capillary column gas chromatographic method, in splitless mode, for analysing of the three chloroanthracene isomers is described. The method affords efficient separation and good linearity for each isomer in the range of 0.2 -200 μg/ml. The method can also be used in separation and determination of another thirty three aromatic and their halosubstituted compounds. This paper also presents the applications of the method in analysing of complex products mixture from reaction of the selected aromatic compounds with hydrogen chloride on fly ash surface from municipal incinerator.     

Evaluation of the biodegradability of copolyesters containing aromatic compounds by investigations of model oligomers

Model oligo esters of terephthalic acid with 1,2-ethanediol, 1,3-propanediol, and 1,4-butanediol have been investigated with regard to their biodegradability in different biological environments. Well-characterized oligomers with weight-average molar masses of from 600 to 2600 g/mol exhibit biodegradation in aqueous systems, soil, and compost at 60°C. SEC investigations showed a fast biological degradation of the oligomer fraction consisting of 1 or 2 repeating units, independent of the diol component used for polycondensation, while polyester oligomers with degrees of polymerization higher than 2 were stable against microbial attack at room temperature in a time frame of 2 months. At 60°C in a compost environment chemical hydrolysis also degrades chains longer than two repeating units, resulting in enhanced degradability of the oligomers. Metabolization of the monomers and the dimers as well by the microorganisms could be confirmed by comparing SEC measurements and carbon balances in a Sturm test experiment. Based on these results degradation characteristics of potential oligomer intermediates resulting from a primary chain scission from copolyesters consisting of aromatic and aliphatic dicarbonic acids can be predicted depending on their composition. These results will have an evident influence on the evaluation of the biodegradability of commercially interesting copolyesters and lead to new ways of tailor-made designing of new biodegradable materials as well.     

Control of ammonia toxicity to Hyalella azteca by sodium, potassium and pH

The toxicity of ammonia to Hyalella azteca at constant pH in artificial media was controlled by sodium and potassium, and not by calcium, magnesium, or anions. Small increases in the LC50 for total ammonia (from 0.15 to 0.5 mM) occurred as sodium was increased from 0.1 to 1 mM and above, but major increases in the LC50 (to over 10 mM total ammonia) required the addition of potassium. Potassium was, however, more effective at reducing ammonia toxicity at high (1 mM) sodium than at low (0.1 mM) sodium. Ammonia toxicity was independent of pH at low sodium and potassium concentrations, when ammonia toxicity appeared to be associated primarily with aqueous ammonium ion concentrations. At high sodium and potassium concentrations, the toxicity of ammonia was reduced to the point where un-ionized ammonia concentrations also affected toxicity, and the LC50 became pH dependent. A mathematical model was produced for predicting ammonia toxicity from sodium and potassium concentrations and pH.     

Practical evaluation of a pilot immunization campaign against typhoid Fever in a cambodian refugee cAMP

An epidemic outbreak of typhoid fever in the largest refugee camp of the besieged capital of Phom-Penh, Cambodia; the concomitant lack of personal and public hygiene and the availability of a locally manufactured Tetanus-Typhoid-Paratyphoid vaccine, prompted us to test the practicability of a mass immunization campaign by carrying out a trial in the smaller, well delineated refugee camp of Pochentong. Attendances by adults as well as children throughout the three or four inoculation rounds showed a steady decline with only 30 (20%) of the people completing the course. The general initial acceptance by the people on the other hand was good, due to a comprehensive service (information, health education and individual care of patients). It is concluded from these results that multi-injection immunization campaigns against typhoid-paratyphoid are a waste of money in a war-torn situation with an unstable population.